Dopamine agonists, such as bromocriptine, and muscle relaxants, such as dantrolene, are often used in the treatment of NMS, however, their effectiveness has not been demonstrated in controlled studies. Cardiovascular: cardiac irregularities and or palpitation, orthostatic effects including hypotensive episodes, hypertension, phlebitis. By reducing certain adverse reactions produced by levodopa alone, SINEMET permits more patients to obtain adequate relief of the symptoms of Parkinson disease. No effect on et carbidopa laupaev kattetoimetusviisi mortality or incidence and type of neoplasia was seen when compared to concurrent controls. If general anesthesia is required, SINEMET may be continued as long as the patient is permitted to take fluids and medication by mouth. Patients should be advised that occasionally, dark color red, brown, or black may appear in saliva, urine, or sweat after ingestion of SINEMET. In the event of overdosage, general supportive measures should be employed, along with immediate gastric lavage.
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